Meta-analysis or meta-synthesis and how it informs evidence-based practice

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Consider the purpose and process of meta-analysis or meta-synthesis and how it informs evidence-based practice. How do recommendations made on the basis of these meta-analyses work to improve quality of care? Why would basing a practice change on one research article be unreliable? For additional details, please refer to the Journal Assignment
Guidelines and Rubric document. Please refer to writer’s message for more details.